| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0463 | nadK | THII_0463 | THII_2713 | Bifunctional malic enzyme oxidoreductase/phosphotransacetylase. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.473 |
| THII_2118 | nadK | THII_2118 | THII_2713 | Inositol monophosphatase. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.583 |
| THII_2760 | THII_2761 | THII_2760 | THII_2761 | NAD(P)(+) transhydrogenase. | NAD(P) transhydrogenase. | 0.998 |
| THII_2760 | THII_2762 | THII_2760 | THII_2762 | NAD(P)(+) transhydrogenase. | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| THII_2760 | nadD | THII_2760 | THII_3906 | NAD(P)(+) transhydrogenase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
| THII_2760 | nadE | THII_2760 | THII_3080 | NAD(P)(+) transhydrogenase. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.905 |
| THII_2760 | nadK | THII_2760 | THII_2713 | NAD(P)(+) transhydrogenase. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.913 |
| THII_2761 | THII_2760 | THII_2761 | THII_2760 | NAD(P) transhydrogenase. | NAD(P)(+) transhydrogenase. | 0.998 |
| THII_2761 | THII_2762 | THII_2761 | THII_2762 | NAD(P) transhydrogenase. | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| THII_2761 | nadD | THII_2761 | THII_3906 | NAD(P) transhydrogenase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
| THII_2761 | nadE | THII_2761 | THII_3080 | NAD(P) transhydrogenase. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.905 |
| THII_2761 | nadK | THII_2761 | THII_2713 | NAD(P) transhydrogenase. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.913 |
| THII_2762 | THII_2760 | THII_2762 | THII_2760 | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P)(+) transhydrogenase. | 0.999 |
| THII_2762 | THII_2761 | THII_2762 | THII_2761 | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P) transhydrogenase. | 0.999 |
| THII_2762 | nadD | THII_2762 | THII_3906 | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
| THII_2762 | nadE | THII_2762 | THII_3080 | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.932 |
| THII_2762 | nadK | THII_2762 | THII_2713 | NADP transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.904 |
| THII_3016 | nadK | THII_3016 | THII_2713 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.855 |
| dxs | nadE | THII_1465 | THII_3080 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.416 |
| dxs | nadK | THII_1465 | THII_2713 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.612 |