Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
THII_2988Hydroxyacid dehydrogenase. (323 aa)    
Predicted Functional Partners:
THII_3339
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.909
THII_0463
Bifunctional malic enzyme oxidoreductase/phosphotransacetylase.
  
 
 0.907
THII_1025
Metallo-beta-lactamase family protein.
    
 0.907
THII_3499
Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.903
THII_3694
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
   
 
 0.903
THII_3692
Pyruvate:ferredoxin oxidoreductase, beta subunit.
   
 
  0.901
THII_2622
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
  0.900
THII_3693
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
     
 0.900
THII_2331
Acetolactate synthase, small subunit.
  
 
 0.851
THII_1889
Serine--pyruvate transaminase.
  
 
 0.840
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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