| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_2182 | THII_3035 | THII_2182 | THII_3035 | Ketohexokinase. | PfkB domain-containing protein. | 0.903 |
| THII_2182 | hisA | THII_2182 | THII_1333 | Ketohexokinase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase (EC:5.3.1.16). | 0.538 |
| THII_2909 | THII_3035 | THII_2909 | THII_3035 | Phosphotransferase system, mannose/fructose-specific component IIA. | PfkB domain-containing protein. | 0.813 |
| THII_2909 | THII_3057 | THII_2909 | THII_3057 | Phosphotransferase system, mannose/fructose-specific component IIA. | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.917 |
| THII_3035 | THII_2182 | THII_3035 | THII_2182 | PfkB domain-containing protein. | Ketohexokinase. | 0.903 |
| THII_3035 | THII_2909 | THII_3035 | THII_2909 | PfkB domain-containing protein. | Phosphotransferase system, mannose/fructose-specific component IIA. | 0.813 |
| THII_3035 | THII_3057 | THII_3035 | THII_3057 | PfkB domain-containing protein. | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.919 |
| THII_3035 | glmS | THII_3035 | THII_3634 | PfkB domain-containing protein. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.905 |
| THII_3035 | hisA | THII_3035 | THII_1333 | PfkB domain-containing protein. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase (EC:5.3.1.16). | 0.538 |
| THII_3035 | pfp | THII_3035 | THII_0379 | PfkB domain-containing protein. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.918 |
| THII_3035 | pgi | THII_3035 | THII_1441 | PfkB domain-containing protein. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.924 |
| THII_3035 | zwf | THII_3035 | THII_0436 | PfkB domain-containing protein. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.460 |
| THII_3057 | THII_2909 | THII_3057 | THII_2909 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphotransferase system, mannose/fructose-specific component IIA. | 0.917 |
| THII_3057 | THII_3035 | THII_3057 | THII_3035 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | PfkB domain-containing protein. | 0.919 |
| THII_3057 | glmS | THII_3057 | THII_3634 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.925 |
| THII_3057 | pfp | THII_3057 | THII_0379 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.928 |
| THII_3057 | pgi | THII_3057 | THII_1441 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.959 |
| THII_3057 | zwf | THII_3057 | THII_0436 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.531 |
| glmS | THII_3035 | THII_3634 | THII_3035 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | PfkB domain-containing protein. | 0.905 |
| glmS | THII_3057 | THII_3634 | THII_3057 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.925 |