| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0199 | THII_3187 | THII_0199 | THII_3187 | DNA internalization-related competence protein ComEC/Rec2. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.531 |
| THII_0199 | recA | THII_0199 | THII_1413 | DNA internalization-related competence protein ComEC/Rec2. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.621 |
| THII_1718 | THII_3187 | THII_1718 | THII_3187 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.882 |
| THII_2338 | THII_2352 | THII_2338 | THII_2352 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.978 |
| THII_2338 | THII_3187 | THII_2338 | THII_3187 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.928 |
| THII_2338 | nadD | THII_2338 | THII_3906 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.958 |
| THII_2338 | nadE | THII_2338 | THII_3080 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.775 |
| THII_2338 | surE | THII_2338 | THII_1715 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.902 |
| THII_2352 | THII_2338 | THII_2352 | THII_2338 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.978 |
| THII_2352 | THII_3187 | THII_2352 | THII_3187 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.922 |
| THII_2352 | nadD | THII_2352 | THII_3906 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.950 |
| THII_2352 | nadE | THII_2352 | THII_3080 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.612 |
| THII_2352 | surE | THII_2352 | THII_1715 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.905 |
| THII_3185 | THII_3187 | THII_3185 | THII_3187 | U32 family peptidase. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.619 |
| THII_3185 | speA | THII_3185 | THII_3186 | U32 family peptidase. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.718 |
| THII_3187 | THII_0199 | THII_3187 | THII_0199 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | DNA internalization-related competence protein ComEC/Rec2. | 0.531 |
| THII_3187 | THII_1718 | THII_3187 | THII_1718 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.882 |
| THII_3187 | THII_2338 | THII_3187 | THII_2338 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.928 |
| THII_3187 | THII_2352 | THII_3187 | THII_2352 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.922 |
| THII_3187 | THII_3185 | THII_3187 | THII_3185 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | U32 family peptidase. | 0.619 |