| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0936 | THII_3323 | THII_0936 | THII_3323 | NUDIX hydrolase. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.902 |
| THII_0936 | folE2 | THII_0936 | THII_1466 | NUDIX hydrolase. | Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.911 |
| THII_3322 | THII_3323 | THII_3322 | THII_3323 | Binding-protein-dependent transporters inner membrane component. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.590 |
| THII_3322 | THII_3324 | THII_3322 | THII_3324 | Binding-protein-dependent transporters inner membrane component. | Secreted protein. | 0.567 |
| THII_3322 | THII_3325 | THII_3322 | THII_3325 | Binding-protein-dependent transporters inner membrane component. | Invasion gene expression up-regulator SirB. | 0.567 |
| THII_3323 | THII_0936 | THII_3323 | THII_0936 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | NUDIX hydrolase. | 0.902 |
| THII_3323 | THII_3322 | THII_3323 | THII_3322 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Binding-protein-dependent transporters inner membrane component. | 0.590 |
| THII_3323 | THII_3324 | THII_3323 | THII_3324 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Secreted protein. | 0.741 |
| THII_3323 | THII_3325 | THII_3323 | THII_3325 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Invasion gene expression up-regulator SirB. | 0.741 |
| THII_3323 | THII_3347 | THII_3323 | THII_3347 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | MscS Mechanosensitive ion channel. | 0.522 |
| THII_3323 | cysS | THII_3323 | THII_2971 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.553 |
| THII_3323 | folE2 | THII_3323 | THII_1466 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.924 |
| THII_3323 | queC | THII_3323 | THII_0764 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | ExsB family protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.927 |
| THII_3323 | queE | THII_3323 | THII_0931 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.993 |
| THII_3323 | queF | THII_3323 | THII_1250 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.811 |
| THII_3324 | THII_3322 | THII_3324 | THII_3322 | Secreted protein. | Binding-protein-dependent transporters inner membrane component. | 0.567 |
| THII_3324 | THII_3323 | THII_3324 | THII_3323 | Secreted protein. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.741 |
| THII_3324 | THII_3325 | THII_3324 | THII_3325 | Secreted protein. | Invasion gene expression up-regulator SirB. | 0.773 |
| THII_3325 | THII_3322 | THII_3325 | THII_3322 | Invasion gene expression up-regulator SirB. | Binding-protein-dependent transporters inner membrane component. | 0.567 |
| THII_3325 | THII_3323 | THII_3325 | THII_3323 | Invasion gene expression up-regulator SirB. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.741 |