STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (324 aa)    
Predicted Functional Partners:
THII_3214
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.996
THII_3783
Citrate synthase; Belongs to the citrate synthase family.
  
 0.989
THII_0463
Bifunctional malic enzyme oxidoreductase/phosphotransacetylase.
  
 0.965
THII_3572
Isocitrate dehydrogenase, NADP-dependent.
  
 
 0.940
THII_0534
Malate synthase A; Belongs to the malate synthase family.
   
 0.936
THII_3762
Aspartate aminotransferase.
  
 0.932
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.929
THII_3728
Glutamate synthase.
  
 
 0.888
THII_1445
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.867
THII_1862
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
  
  
 0.860
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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