Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (324 aa)    
Predicted Functional Partners:
THII_3783
Citrate synthase; Belongs to the citrate synthase family.
  
 0.997
THII_3214
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.995
THII_0463
Bifunctional malic enzyme oxidoreductase/phosphotransacetylase.
  
 0.989
THII_3572
Isocitrate dehydrogenase, NADP-dependent.
  
 0.971
THII_2208
Polyketide synthase.
  
 0.947
THII_1445
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.945
THII_0534
Malate synthase A; Belongs to the malate synthase family.
   
 0.936
THII_3762
Aspartate aminotransferase.
  
 0.929
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.927
THII_2201
FkbH-like protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.919
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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