| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0353 | THII_1200 | THII_0353 | THII_1200 | N-carbamoylputrescine amidase. | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | 0.474 |
| THII_0353 | THII_3051 | THII_0353 | THII_3051 | N-carbamoylputrescine amidase. | Putative spermidine synthase with an N-terminal membrane domain. | 0.924 |
| THII_0353 | speE | THII_0353 | THII_3766 | N-carbamoylputrescine amidase. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.953 |
| THII_1200 | THII_0353 | THII_1200 | THII_0353 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | N-carbamoylputrescine amidase. | 0.474 |
| THII_1200 | speE | THII_1200 | THII_3766 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.781 |
| THII_3051 | THII_0353 | THII_3051 | THII_0353 | Putative spermidine synthase with an N-terminal membrane domain. | N-carbamoylputrescine amidase. | 0.924 |
| THII_3051 | mtaD | THII_3051 | THII_3021 | Putative spermidine synthase with an N-terminal membrane domain. | N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.907 |
| THII_3051 | speD | THII_3051 | THII_3899 | Putative spermidine synthase with an N-terminal membrane domain. | S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.988 |
| THII_3051 | speE | THII_3051 | THII_3766 | Putative spermidine synthase with an N-terminal membrane domain. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.929 |
| THII_3767 | mnmG | THII_3767 | THII_3765 | Hypothetical protein. | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.406 |
| THII_3767 | speE | THII_3767 | THII_3766 | Hypothetical protein. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.534 |
| mnmG | THII_3767 | THII_3765 | THII_3767 | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Hypothetical protein. | 0.406 |
| mnmG | speE | THII_3765 | THII_3766 | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.594 |
| mtaD | THII_3051 | THII_3021 | THII_3051 | N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Putative spermidine synthase with an N-terminal membrane domain. | 0.907 |
| mtaD | speE | THII_3021 | THII_3766 | N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.907 |
| mtnA | speD | THII_1317 | THII_3899 | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.421 |
| mtnA | speE | THII_1317 | THII_3766 | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.483 |
| speA | speE | THII_3186 | THII_3766 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.653 |
| speD | THII_3051 | THII_3899 | THII_3051 | S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | Putative spermidine synthase with an N-terminal membrane domain. | 0.988 |
| speD | mtnA | THII_3899 | THII_1317 | S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.421 |