Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
THII_3809Cobyrinic acid a,c-diamide synthase. (476 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 0.951
THII_3299
Cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
 
  
 0.936
THII_0611
Sulfite reductase, dissimilatory-type subunit alpha.
 
   
 0.715
THII_0612
Sulfite reductase, dissimilatory-type subunit beta.
 
   
 0.712
THII_3808
Protein involved in sulfur oxidation DsrR.
     
 0.658
THII_3810
OmpA family protein.
       0.658
THII_0617
Electron transport protein DsrM.
 
   
 0.629
THII_0618
Electron transport protein DsrK.
 
   
 0.588
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
   
 0.584
THII_0622
Electron transport protein DsrP.
 
   
 0.579
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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