node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MED16 | X975_11761 | A0A087T099 | A0A087SWZ0 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Elongation of very long chain fatty acids protein. | 0.551 |
X975_01997 | X975_08672 | A0A087T2S1 | A0A087TNS1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of very long chain fatty acids protein. | 0.846 |
X975_01997 | X975_11761 | A0A087T2S1 | A0A087SWZ0 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of very long chain fatty acids protein. | 0.662 |
X975_01997 | X975_12039 | A0A087T2S1 | A0A087UAX4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of very long chain fatty acids protein. | 0.845 |
X975_01997 | X975_13791 | A0A087T2S1 | A0A087TT45 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.839 |
X975_01997 | X975_14594 | A0A087T2S1 | A0A087SY46 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Trans-2,3-enoyl-CoA reductase. | 0.996 |
X975_01997 | X975_21445 | A0A087T2S1 | A0A087TE05 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Estradiol 17-beta-dehydrogenase 12. | 0.951 |
X975_01997 | X975_24498 | A0A087T2S1 | A0A087U100 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Hydroxysteroid dehydrogenase-like protein 1. | 0.964 |
X975_04485 | X975_11761 | A0A087T097 | A0A087SWZ0 | Mediator of RNA polymerase II transcription subunit 16. | Elongation of very long chain fatty acids protein. | 0.551 |
X975_08672 | X975_01997 | A0A087TNS1 | A0A087T2S1 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.846 |
X975_08672 | X975_09393 | A0A087TNS1 | A0A087TTD2 | Elongation of very long chain fatty acids protein. | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial. | 0.826 |
X975_08672 | X975_11761 | A0A087TNS1 | A0A087SWZ0 | Elongation of very long chain fatty acids protein. | Elongation of very long chain fatty acids protein. | 0.618 |
X975_08672 | X975_12039 | A0A087TNS1 | A0A087UAX4 | Elongation of very long chain fatty acids protein. | Elongation of very long chain fatty acids protein. | 0.878 |
X975_08672 | X975_13791 | A0A087TNS1 | A0A087TT45 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.899 |
X975_08672 | X975_14594 | A0A087TNS1 | A0A087SY46 | Elongation of very long chain fatty acids protein. | Trans-2,3-enoyl-CoA reductase. | 0.916 |
X975_08672 | X975_21445 | A0A087TNS1 | A0A087TE05 | Elongation of very long chain fatty acids protein. | Estradiol 17-beta-dehydrogenase 12. | 0.770 |
X975_08672 | X975_24498 | A0A087TNS1 | A0A087U100 | Elongation of very long chain fatty acids protein. | Hydroxysteroid dehydrogenase-like protein 1. | 0.770 |
X975_09393 | X975_08672 | A0A087TTD2 | A0A087TNS1 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial. | Elongation of very long chain fatty acids protein. | 0.826 |
X975_09393 | X975_11761 | A0A087TTD2 | A0A087SWZ0 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial. | Elongation of very long chain fatty acids protein. | 0.596 |
X975_09393 | X975_12039 | A0A087TTD2 | A0A087UAX4 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial. | Elongation of very long chain fatty acids protein. | 0.849 |