X975_09521 protein (Stegodyphus mimosarum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

X975_09521

Abhydrolase domain-containing protein 14A. (192 aa)

Predicted Functional Partners:

X975_24763

0.787

X975_09506

0.787

X975_12096

0.707

X975_00443

0.695

X975_10793

0.689

X975_15703

0.627

X975_15704

0.627

X975_19398

0.627

X975_07114

0.627

X975_02565

0.627

Your Current Organism:

Stegodyphus mimosarum

NCBI taxonomy Id: 407821
Other names: S. mimosarum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
X975_00443	X975_09506	A0A087UMC8	A0A087TWS5	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.684
X975_00443	X975_09521	A0A087UMC8	A0A087T7K8	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Abhydrolase domain-containing protein 14A.	0.695
X975_00443	X975_10793	A0A087UMC8	A0A087TDV1	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit gamma, mitochondrial.	0.999
X975_00443	X975_24763	A0A087UMC8	A0A087TQ12	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.684
X975_02565	X975_09521	A0A087UCH6	A0A087T7K8	Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform.	Abhydrolase domain-containing protein 14A.	0.627
X975_07114	X975_09521	A0A087U8N2	A0A087T7K8	Serine/threonine-protein phosphatase 4 regulatory subunit 1.	Abhydrolase domain-containing protein 14A.	0.627
X975_09506	X975_00443	A0A087TWS5	A0A087UMC8	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.684
X975_09506	X975_09521	A0A087TWS5	A0A087T7K8	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Abhydrolase domain-containing protein 14A.	0.787
X975_09506	X975_10793	A0A087TWS5	A0A087TDV1	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	ATP synthase subunit gamma, mitochondrial.	0.884
X975_09506	X975_12096	A0A087TWS5	A0A087UMC4	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Hydroxysteroid dehydrogenase-like protein 2.	0.926
X975_09521	X975_00443	A0A087T7K8	A0A087UMC8	Abhydrolase domain-containing protein 14A.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.695
X975_09521	X975_02565	A0A087T7K8	A0A087UCH6	Abhydrolase domain-containing protein 14A.	Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform.	0.627
X975_09521	X975_07114	A0A087T7K8	A0A087U8N2	Abhydrolase domain-containing protein 14A.	Serine/threonine-protein phosphatase 4 regulatory subunit 1.	0.627
X975_09521	X975_09506	A0A087T7K8	A0A087TWS5	Abhydrolase domain-containing protein 14A.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.787
X975_09521	X975_10793	A0A087T7K8	A0A087TDV1	Abhydrolase domain-containing protein 14A.	ATP synthase subunit gamma, mitochondrial.	0.689
X975_09521	X975_12096	A0A087T7K8	A0A087UMC4	Abhydrolase domain-containing protein 14A.	Hydroxysteroid dehydrogenase-like protein 2.	0.707
X975_09521	X975_15703	A0A087T7K8	A0A087T1Z0	Abhydrolase domain-containing protein 14A.	LisH domain and HEAT repeat-containing protein-like protein.	0.627
X975_09521	X975_15704	A0A087T7K8	A0A087T1Z1	Abhydrolase domain-containing protein 14A.	LisH domain and HEAT repeat-containing protein.	0.627
X975_09521	X975_19398	A0A087T7K8	A0A087U5A8	Abhydrolase domain-containing protein 14A.	Serine/threonine-protein phosphatase 4 regulatory subunit 1.	0.627
X975_09521	X975_24763	A0A087T7K8	A0A087TQ12	Abhydrolase domain-containing protein 14A.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.787

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

52

average node degree:

9.45

avg. local clustering coefficient:

0.958

expected number of edges:

14

PPI enrichment p-value:

1.12e-14

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042073

Intraciliary transport

5 of 24

2.5

4.01

1.70e-08

GO:0060271

Cilium assembly

6 of 114

1.9

3.09

6.86e-08

GO:0007017

Microtubule-based process

6 of 255

1.55

2.12

1.54e-06

GO:0048736

Appendage development

2 of 7

2.64

1.46

0.0021

GO:0048513

Animal organ development

3 of 66

1.84

1.37

0.0017

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030992

Intraciliary transport particle B

7 of 16

2.82

7.82

8.84e-16

GO:0036064

Ciliary basal body

6 of 41

2.35

5.02

4.29e-11

GO:0005929

Cilium

7 of 186

1.76

3.27

1.54e-09

GO:0005813

Centrosome

5 of 77

1.99

3.15

1.13e-07

GO:0005814

Centriole

3 of 31

2.17

2.07

9.08e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1366

Intraciliary transport particle B

7 of 13

2.91

7.99

6.53e-16

CL:1337

Intraciliary transport particle, and Ankyrin repeat

8 of 52

2.37

6.8

2.02e-15

CL:1368

Intraciliary transport particle B

3 of 5

2.96

3.19

1.47e-06

CL:11887

Mixed, incl. Glycerophosphodiester phosphodiesterase domain, and SPX domain

2 of 6

2.7

1.58

0.0013

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5620924

Intraflagellar transport

7 of 33

2.51

6.45

7.96e-14

MAP-5617833

Cilium Assembly

7 of 111

1.98

4.15

1.11e-10

MAP-1852241

Organelle biogenesis and maintenance

7 of 130

1.91

3.89

2.14e-10

MAP-5610787

Hedgehog off state

4 of 48

2.1

2.56

6.38e-06

MAP-5358351

Signaling by Hedgehog

4 of 100

1.78

1.86

8.52e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03009

Glycerophosphoryl diester phosphodiesterase family

2 of 6

2.7

1.04

0.0132

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030395

Glycerophosphodiester phosphodiesterase domain

2 of 6

2.7

0.81

0.0348

IPR017946

PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily

2 of 8

2.58

0.8

0.0348

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (24%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About