node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MED16 | X975_12385 | A0A087T099 | A0A087T885 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.518 |
MED16 | X975_12386 | A0A087T099 | A0A087T886 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.518 |
X975_00438 | X975_12385 | A0A087TJA8 | A0A087T885 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.908 |
X975_03413 | X975_12385 | A0A087TYW5 | A0A087T885 | Rhomboid domain-containing protein 1. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.521 |
X975_03413 | X975_12386 | A0A087TYW5 | A0A087T886 | Rhomboid domain-containing protein 1. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.521 |
X975_04485 | X975_12385 | A0A087T097 | A0A087T885 | Mediator of RNA polymerase II transcription subunit 16. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.518 |
X975_04485 | X975_12386 | A0A087T097 | A0A087T886 | Mediator of RNA polymerase II transcription subunit 16. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.518 |
X975_12385 | MED16 | A0A087T885 | A0A087T099 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.518 |
X975_12385 | X975_00438 | A0A087T885 | A0A087TJA8 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.908 |
X975_12385 | X975_03413 | A0A087T885 | A0A087TYW5 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Rhomboid domain-containing protein 1. | 0.521 |
X975_12385 | X975_04485 | A0A087T885 | A0A087T097 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Mediator of RNA polymerase II transcription subunit 16. | 0.518 |
X975_12385 | X975_12386 | A0A087T885 | A0A087T886 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.920 |
X975_12385 | X975_14436 | A0A087T885 | A0A087SYP0 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.832 |
X975_12385 | X975_16634 | A0A087T885 | A0A087UMV9 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Phosphatidate phosphatase PPAPDC1B. | 0.553 |
X975_12385 | X975_17865 | A0A087T885 | A0A087TJZ2 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Transposable element Tcb2 transposase. | 0.518 |
X975_12385 | X975_21384 | A0A087T885 | A0A087SZY2 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Lipid phosphate phosphohydrolase 1. | 0.553 |
X975_12385 | X975_21817 | A0A087T885 | A0A087TI98 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Coiled-coil domain-containing protein 115. | 0.553 |
X975_12386 | MED16 | A0A087T886 | A0A087T099 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.518 |
X975_12386 | X975_03413 | A0A087T886 | A0A087TYW5 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Rhomboid domain-containing protein 1. | 0.521 |
X975_12386 | X975_04485 | A0A087T886 | A0A087T097 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | Mediator of RNA polymerase II transcription subunit 16. | 0.518 |