node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | X975_00515 | A0A087UTA1 | A0A087SWJ6 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | X975_00827 | A0A087UTA1 | A0A087TLT4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 4. | 0.998 |
MCM7 | X975_01278 | A0A087UTA1 | A0A087UT71 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | X975_06769 | A0A087UTA1 | A0A087U833 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein 6-like protein. | 0.999 |
MCM7 | X975_20340 | A0A087UTA1 | A0A087V0G2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.994 |
MCM7 | X975_20341 | A0A087UTA1 | A0A087V0G3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.994 |
MCM7 | X975_21121 | A0A087UTA1 | A0A087T0L8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication factor Cdt1. | 0.999 |
MCM7 | X975_22068 | A0A087UTA1 | A0A087T2T8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 2. | 0.999 |
MCM7 | X975_23187 | A0A087UTA1 | A0A087TWV8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 3. | 0.971 |
MCM7 | X975_23644 | A0A087UTA1 | A0A087SZD0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 5. | 0.998 |
X975_00515 | MCM7 | A0A087SWJ6 | A0A087UTA1 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
X975_00515 | X975_00827 | A0A087SWJ6 | A0A087TLT4 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 4. | 0.998 |
X975_00515 | X975_01278 | A0A087SWJ6 | A0A087UT71 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
X975_00515 | X975_06769 | A0A087SWJ6 | A0A087U833 | DNA helicase; Belongs to the MCM family. | Cell division control protein 6-like protein. | 0.999 |
X975_00515 | X975_20340 | A0A087SWJ6 | A0A087V0G2 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
X975_00515 | X975_20341 | A0A087SWJ6 | A0A087V0G3 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
X975_00515 | X975_21121 | A0A087SWJ6 | A0A087T0L8 | DNA helicase; Belongs to the MCM family. | DNA replication factor Cdt1. | 0.999 |
X975_00515 | X975_22068 | A0A087SWJ6 | A0A087T2T8 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 2. | 0.999 |
X975_00515 | X975_23187 | A0A087SWJ6 | A0A087TWV8 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 3. | 0.973 |
X975_00515 | X975_23644 | A0A087SWJ6 | A0A087SZD0 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 5. | 0.998 |