STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
X975_14258Exonuclease 3'-5' domain-containing protein 2. (562 aa)    
Predicted Functional Partners:
X975_16267
Replication protein A subunit.
    
 0.857
X975_14131
Flap endonuclease 1.
   
 0.819
X975_15981
Replication protein A DNA-binding subunit.
    
 0.776
X975_23430
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.776
X975_11546
DNA2-like helicase.
   
 
 0.767
X975_04326
Exonuclease 1.
   
 0.757
X975_04327
Exonuclease 1.
   
 0.757
X975_19806
BRCA1-associated RING domain protein 1.
    
 0.742
X975_12714
Proliferating cell nuclear antigen.
   
  0.740
X975_12715
Proliferating cell nuclear antigen.
   
  0.740
Your Current Organism:
Stegodyphus mimosarum
NCBI taxonomy Id: 407821
Other names: S. mimosarum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.