Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKG42192.1CalR6 protein. (507 aa)    
Predicted Functional Partners:
AKG42193.1
Peptidase U62 modulator of DNA gyrase.
 
     0.965
AKG42194.1
Hypothetical protein.
       0.773
AKG42195.1
tyrosyl-tRNA synthetase.
       0.755
AKG42189.1
3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.520
AKG44903.1
Flavoprotein disulfide reductase.
      
 0.507
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.505
egtB
TIGR03440 family protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
     
 0.504
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
      
 0.501
AKG42191.1
RDD domain containing protein.
       0.492
AKG46711.1
Amidinotransferase.
      
 0.470
Your Current Organism:
Streptomyces xiamenensis
NCBI taxonomy Id: 408015
Other names: CGMCC 4.3534, DSM 41903, JCM 16123, MCCC 1A01550, S. xiamenensis, Streptomyces sp. 1A01550, Streptomyces sp. USC025, Streptomyces sp. USC026, Streptomyces sp. VJPR-24, Streptomyces xiamenensis Xu et al. 2009
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