node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | purD | SXIM_33400 | SXIM_29050 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.949 |
guaA | purE | SXIM_33400 | SXIM_18480 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.739 |
guaA | purF | SXIM_33400 | SXIM_29440 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.832 |
guaA | purH | SXIM_33400 | SXIM_33930 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.944 |
guaA | purK | SXIM_33400 | SXIM_18490 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.767 |
guaA | purL | SXIM_33400 | SXIM_29220 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.940 |
guaA | purM | SXIM_33400 | SXIM_29450 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole synthetase. | 0.751 |
guaA | purN | SXIM_33400 | SXIM_33920 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.672 |
guaA | purQ | SXIM_33400 | SXIM_29210 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase i; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.770 |
guaA | purS | SXIM_33400 | SXIM_29200 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.577 |
purD | guaA | SXIM_29050 | SXIM_33400 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.949 |
purD | purE | SXIM_29050 | SXIM_18480 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | SXIM_29050 | SXIM_29440 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
purD | purH | SXIM_29050 | SXIM_33930 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.987 |
purD | purK | SXIM_29050 | SXIM_18490 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.971 |
purD | purL | SXIM_29050 | SXIM_29220 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.980 |
purD | purM | SXIM_29050 | SXIM_29450 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole synthetase. | 0.999 |
purD | purN | SXIM_29050 | SXIM_33920 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | SXIM_29050 | SXIM_29210 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase i; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.973 |
purD | purS | SXIM_29050 | SXIM_29200 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.942 |