STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (234 aa)    
Predicted Functional Partners:
AKG44068.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.928
AKG42635.1
Phosphoglycerate mutase.
  
 
 0.922
AKG44034.1
Transcriptional regulator.
  
 
 0.915
AKG46535.1
Long-chain-fatty-acid--CoA ligase.
  
 
 0.915
AKG46592.1
Aminotransferase.
  
 
 0.915
AKG43043.1
AMP-binding enzyme.
  
 
 0.907
AKG46654.1
NRPS protein.
  
 
 0.906
AKG41582.1
Peptide synthetase NRPS5-4-3.
  
 
 0.901
AKG45947.1
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family.
     
 0.813
AKG45946.1
Antibiotic biosynthesis monooxygenase.
       0.754
Your Current Organism:
Streptomyces xiamenensis
NCBI taxonomy Id: 408015
Other names: CGMCC 4.3534, DSM 41903, JCM 16123, MCCC 1A01550, S. xiamenensis, Streptomyces sp. 1A01550, Streptomyces sp. USC025, Streptomyces sp. USC026, Streptomyces sp. VJPR-24, Streptomyces xiamenensis Xu et al. 2009
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