STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA52872.1Hypothetical protein. (380 aa)    
Predicted Functional Partners:
SEA20357.1
Topoisomerase-4 subunit B.
    
 
 0.821
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.821
SEA52894.1
CarboxypepD_reg-like domain-containing protein.
 
    
0.740
SEA52918.1
FecR family protein.
 
     0.722
SEA52936.1
RNA polymerase sigma-70 factor, ECF subfamily.
 
   0.717
SEA53638.1
LysM domain-containing protein.
   
 
 0.711
SEA52853.1
Hypothetical protein.
       0.642
SEA67205.1
PAS domain S-box-containing protein.
    
 0.613
SEA47655.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.602
SEA70388.1
WD40-like Beta Propeller Repeat.
 
 
 
 0.570
Your Current Organism:
Chitinophaga terrae
NCBI taxonomy Id: 408074
Other names: C. terrae Kim and Jung 2007, CIP 109744, Chitinophaga sp. KP01, Chitinophaga terrae Kim and Jung 2007, DSM 23920, KCTC 12836, LMG 24015, LMG:24015, strain KP01
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.