STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A3Q7EUH2Topo-VIb_trans domain-containing protein. (411 aa)    
Predicted Functional Partners:
A0A3Q7EB02
HATPase_c domain-containing protein.
 
     0.951
TOP6A
DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
 
 
 0.874
A0A3Q7HUG7
TP6A_N domain-containing protein.
 
 
 0.797
A0A3Q7HFV0
TP6A_N domain-containing protein.
 
 
 0.789
A0A3Q7FFF7
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.439
A0A3Q7GDF8
Uncharacterized protein.
  
   
 0.428
A0A3Q7G0A7
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
      
 0.420
A0A3Q7HWP8
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.420
A0A3Q7I6I2
Uncharacterized protein.
     
 0.420
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.