node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MPLB_2040061 | MPLB_240004 | MPLB_2040061 | MPLB_240004 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Heat shock protein 70. | 0.868 |
MPLB_2040061 | dnaK | MPLB_2040061 | MPLB_1570027 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.932 |
MPLB_2040061 | groL-2 | MPLB_2040061 | MPLB_1640049 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.561 |
MPLB_2040061 | groS | MPLB_2040061 | MPLB_1990014 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.992 |
MPLB_2040061 | grpE | MPLB_2040061 | MPLB_40047 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.938 |
MPLB_2040061 | hslU | MPLB_2040061 | MPLB_20052 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.752 |
MPLB_2040061 | htpG | MPLB_2040061 | MPLB_500003 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.869 |
MPLB_240004 | MPLB_2040061 | MPLB_240004 | MPLB_2040061 | Heat shock protein 70. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.868 |
MPLB_240004 | MPLB_500007 | MPLB_240004 | MPLB_500007 | Heat shock protein 70. | Cpn60 chaperonin GroEL, large subunit of GroESL. | 0.868 |
MPLB_240004 | groL | MPLB_240004 | MPLB_100037 | Heat shock protein 70. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.868 |
MPLB_240004 | groL-2 | MPLB_240004 | MPLB_1640049 | Heat shock protein 70. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.868 |
MPLB_240004 | groL-3 | MPLB_240004 | MPLB_1990015 | Heat shock protein 70. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.868 |
MPLB_240004 | groS | MPLB_240004 | MPLB_1990014 | Heat shock protein 70. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.917 |
MPLB_240004 | grpE | MPLB_240004 | MPLB_40047 | Heat shock protein 70. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.996 |
MPLB_240004 | hslU | MPLB_240004 | MPLB_20052 | Heat shock protein 70. | ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.705 |
MPLB_240004 | htpG | MPLB_240004 | MPLB_500003 | Heat shock protein 70. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.999 |
MPLB_500007 | MPLB_240004 | MPLB_500007 | MPLB_240004 | Cpn60 chaperonin GroEL, large subunit of GroESL. | Heat shock protein 70. | 0.868 |
MPLB_500007 | dnaK | MPLB_500007 | MPLB_1570027 | Cpn60 chaperonin GroEL, large subunit of GroESL. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.931 |
MPLB_500007 | groL-2 | MPLB_500007 | MPLB_1640049 | Cpn60 chaperonin GroEL, large subunit of GroESL. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.561 |
MPLB_500007 | groS | MPLB_500007 | MPLB_1990014 | Cpn60 chaperonin GroEL, large subunit of GroESL. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.992 |