Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPLA_1000153-hydroxyisobutyrate dehydrogenase. (312 aa)    
Predicted Functional Partners:
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.
   
 
  0.791
MPLA_580001
Methylmalonate-semialdehyde dehydrogenase.
   
 
  0.788
ttuD
Putative hydroxypyruvate reductase.
 
  
 0.724
MPLA_30122
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.681
MPLA_800004
4-hydroxy-2-oxovalerate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.677
MPLA_1680006
3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.
  
 
 0.674
ehhadh
Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.674
MPLA_2140017
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.673
caiD
Crotonobetainyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
  0.603
MPLA_140299
Enoyl-CoA hydratase/isomerase.
   
 
  0.603
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
Server load: medium (42%) [HD]