| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_100035 | MPLA_100036 | MPLA_100035 | MPLA_100036 | Penicillin-binding protein 1C. | Apple domain-containing protein. | 0.927 |
| MPLA_100035 | ddpX | MPLA_100035 | MPLA_100034 | Penicillin-binding protein 1C. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.786 |
| MPLA_100036 | MPLA_100035 | MPLA_100036 | MPLA_100035 | Apple domain-containing protein. | Penicillin-binding protein 1C. | 0.927 |
| MPLA_100036 | ddpX | MPLA_100036 | MPLA_100034 | Apple domain-containing protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.565 |
| MPLA_1170058 | MPLA_1190086 | MPLA_1170058 | MPLA_1190086 | APH domain-containing protein. | N-acetylmuramoyl-L-alanine amidase domain-containing protein. | 0.522 |
| MPLA_1170058 | MPLA_850018 | MPLA_1170058 | MPLA_850018 | APH domain-containing protein. | ATP-grasp domain-containing protein. | 0.423 |
| MPLA_1170058 | ddlA | MPLA_1170058 | MPLA_1390174 | APH domain-containing protein. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.503 |
| MPLA_1170058 | ddlB | MPLA_1170058 | MPLA_1190103 | APH domain-containing protein. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.423 |
| MPLA_1170058 | ddpX | MPLA_1170058 | MPLA_100034 | APH domain-containing protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.445 |
| MPLA_1190031 | ddpX | MPLA_1190031 | MPLA_100034 | Peptidase_M15_4 domain-containing protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.572 |
| MPLA_1190086 | MPLA_1170058 | MPLA_1190086 | MPLA_1170058 | N-acetylmuramoyl-L-alanine amidase domain-containing protein. | APH domain-containing protein. | 0.522 |
| MPLA_1190086 | anmK | MPLA_1190086 | MPLA_1390139 | N-acetylmuramoyl-L-alanine amidase domain-containing protein. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.492 |
| MPLA_1190086 | ddpX | MPLA_1190086 | MPLA_100034 | N-acetylmuramoyl-L-alanine amidase domain-containing protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.594 |
| MPLA_1350077 | ddpX | MPLA_1350077 | MPLA_100034 | Uncharacterized protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.462 |
| MPLA_850018 | MPLA_1170058 | MPLA_850018 | MPLA_1170058 | ATP-grasp domain-containing protein. | APH domain-containing protein. | 0.423 |
| MPLA_850018 | ddpX | MPLA_850018 | MPLA_100034 | ATP-grasp domain-containing protein. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.649 |
| anmK | MPLA_1190086 | MPLA_1390139 | MPLA_1190086 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramoyl-L-alanine amidase domain-containing protein. | 0.492 |
| anmK | ddpX | MPLA_1390139 | MPLA_100034 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.667 |
| ddlA | MPLA_1170058 | MPLA_1390174 | MPLA_1170058 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | APH domain-containing protein. | 0.503 |
| ddlA | ddlB | MPLA_1390174 | MPLA_1190103 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.888 |