| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_1160004 | MPLA_140107 | MPLA_1160004 | MPLA_140107 | Helicase domain protein. | Putative adenylate cyclase/transcriptional regulator. | 0.850 |
| MPLA_1160004 | rpoA | MPLA_1160004 | MPLA_1830027 | Helicase domain protein. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.970 |
| MPLA_1160004 | rpoB | MPLA_1160004 | MPLA_1820011 | Helicase domain protein. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.979 |
| MPLA_1160004 | rpoC | MPLA_1160004 | MPLA_1820012 | Helicase domain protein. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.942 |
| MPLA_1160004 | rpoZ | MPLA_1160004 | MPLA_1220012 | Helicase domain protein. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.965 |
| MPLA_140107 | MPLA_1160004 | MPLA_140107 | MPLA_1160004 | Putative adenylate cyclase/transcriptional regulator. | Helicase domain protein. | 0.850 |
| MPLA_140107 | cysG | MPLA_140107 | MPLA_1650117 | Putative adenylate cyclase/transcriptional regulator. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.764 |
| MPLA_140107 | ribB | MPLA_140107 | MPLA_1800028 | Putative adenylate cyclase/transcriptional regulator. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.657 |
| MPLA_140107 | rpoA | MPLA_140107 | MPLA_1830027 | Putative adenylate cyclase/transcriptional regulator. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.923 |
| MPLA_140107 | rpoB | MPLA_140107 | MPLA_1820011 | Putative adenylate cyclase/transcriptional regulator. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.911 |
| MPLA_140107 | rpoC | MPLA_140107 | MPLA_1820012 | Putative adenylate cyclase/transcriptional regulator. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
| MPLA_140107 | rpoD | MPLA_140107 | MPLA_80033 | Putative adenylate cyclase/transcriptional regulator. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.850 |
| MPLA_140107 | rpoH | MPLA_140107 | MPLA_180078 | Putative adenylate cyclase/transcriptional regulator. | RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.850 |
| MPLA_140107 | rpoH-2 | MPLA_140107 | MPLA_990004 | Putative adenylate cyclase/transcriptional regulator. | RNA polymerase sigma-32 factor; Belongs to the sigma-70 factor family. | 0.850 |
| MPLA_140107 | rpoZ | MPLA_140107 | MPLA_1220012 | Putative adenylate cyclase/transcriptional regulator. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.689 |
| cysG | MPLA_140107 | MPLA_1650117 | MPLA_140107 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Putative adenylate cyclase/transcriptional regulator. | 0.764 |
| cysG | ribB | MPLA_1650117 | MPLA_1800028 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.409 |
| ribB | MPLA_140107 | MPLA_1800028 | MPLA_140107 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Putative adenylate cyclase/transcriptional regulator. | 0.657 |
| ribB | cysG | MPLA_1800028 | MPLA_1650117 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.409 |
| ribB | rpoB | MPLA_1800028 | MPLA_1820011 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.649 |