guaB protein (Mesorhizobium sp. ORS3359) - STRING interaction network

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guaB

Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)

Predicted Functional Partners:

guaA

0.999

purH

0.995

purA

0.987

MPLA_1650070

0.959

MPLA_1320003

0.953

ribB

0.952

purK

0.946

MPLA_760008

0.941

purM

0.917

purF

0.916

Your Current Organism:

Mesorhizobium sp. ORS3359

NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPLA_1320003	MPLA_1650070	MPLA_1320003	MPLA_1650070	Glutamine amidotransferase class-I.	Glutamine amidotransferase type-1 domain-containing protein.	0.743
MPLA_1320003	guaA	MPLA_1320003	MPLA_1650100	Glutamine amidotransferase class-I.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.701
MPLA_1320003	guaB	MPLA_1320003	MPLA_1540004	Glutamine amidotransferase class-I.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.953
MPLA_1320003	purA	MPLA_1320003	MPLA_590020	Glutamine amidotransferase class-I.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.477
MPLA_1320003	ribB	MPLA_1320003	MPLA_1800028	Glutamine amidotransferase class-I.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.483
MPLA_1650070	MPLA_1320003	MPLA_1650070	MPLA_1320003	Glutamine amidotransferase type-1 domain-containing protein.	Glutamine amidotransferase class-I.	0.743
MPLA_1650070	guaA	MPLA_1650070	MPLA_1650100	Glutamine amidotransferase type-1 domain-containing protein.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.719
MPLA_1650070	guaB	MPLA_1650070	MPLA_1540004	Glutamine amidotransferase type-1 domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.959
MPLA_1650070	purA	MPLA_1650070	MPLA_590020	Glutamine amidotransferase type-1 domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.477
MPLA_1650070	ribB	MPLA_1650070	MPLA_1800028	Glutamine amidotransferase type-1 domain-containing protein.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.483
MPLA_760008	guaB	MPLA_760008	MPLA_1540004	Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.941
guaA	MPLA_1320003	MPLA_1650100	MPLA_1320003	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamine amidotransferase class-I.	0.701
guaA	MPLA_1650070	MPLA_1650100	MPLA_1650070	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamine amidotransferase type-1 domain-containing protein.	0.719
guaA	guaB	MPLA_1650100	MPLA_1540004	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	purA	MPLA_1650100	MPLA_590020	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.965
guaA	purF	MPLA_1650100	MPLA_1250004	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.914
guaA	purH	MPLA_1650100	MPLA_550001	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazolecarboxamide formyltransferase.	0.957
guaA	purK	MPLA_1650100	MPLA_180045	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.756
guaA	purM	MPLA_1650100	MPLA_1280067	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine cyclo-ligase.	0.811
guaA	ribB	MPLA_1650100	MPLA_1800028	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.730

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