| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_1390092 | MPLA_140332 | MPLA_1390092 | MPLA_140332 | Isochorismatase hydrolase. | Aminodeoxychorismate synthase. | 0.709 |
| MPLA_1390092 | trpE(G | MPLA_1390092 | MPLA_160035 | Isochorismatase hydrolase. | Anthranilate synthase. | 0.957 |
| MPLA_140332 | MPLA_1390092 | MPLA_140332 | MPLA_1390092 | Aminodeoxychorismate synthase. | Isochorismatase hydrolase. | 0.709 |
| MPLA_140332 | aroC | MPLA_140332 | MPLA_1800027 | Aminodeoxychorismate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.942 |
| MPLA_140332 | aroE | MPLA_140332 | MPLA_390019 | Aminodeoxychorismate synthase. | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.855 |
| MPLA_140332 | folP | MPLA_140332 | MPLA_970015 | Aminodeoxychorismate synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.853 |
| MPLA_140332 | trpA | MPLA_140332 | MPLA_1170068 | Aminodeoxychorismate synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.961 |
| MPLA_140332 | trpB | MPLA_140332 | MPLA_1170069 | Aminodeoxychorismate synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.974 |
| MPLA_140332 | trpC | MPLA_140332 | MPLA_1830237 | Aminodeoxychorismate synthase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.998 |
| MPLA_140332 | trpD | MPLA_140332 | MPLA_1830236 | Aminodeoxychorismate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
| MPLA_140332 | trpE(G | MPLA_140332 | MPLA_160035 | Aminodeoxychorismate synthase. | Anthranilate synthase. | 0.994 |
| MPLA_140332 | trpF | MPLA_140332 | MPLA_1170070 | Aminodeoxychorismate synthase. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.982 |
| aroC | MPLA_140332 | MPLA_1800027 | MPLA_140332 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase. | 0.942 |
| aroC | aroE | MPLA_1800027 | MPLA_390019 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.960 |
| aroC | trpA | MPLA_1800027 | MPLA_1170068 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.890 |
| aroC | trpB | MPLA_1800027 | MPLA_1170069 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.775 |
| aroC | trpC | MPLA_1800027 | MPLA_1830237 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.802 |
| aroC | trpD | MPLA_1800027 | MPLA_1830236 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.905 |
| aroC | trpE(G | MPLA_1800027 | MPLA_160035 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase. | 0.956 |
| aroC | trpF | MPLA_1800027 | MPLA_1170070 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.705 |