cysH protein (Mesorhizobium sp. ORS3359) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

cysH

Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (254 aa)

Predicted Functional Partners:

MPLA_1650119

0.999

nodQ

0.999

cysD

0.994

cysG

0.988

cysA

0.969

MPLA_20057

0.968

cysW

0.960

cysP

0.955

MPLA_1650121

0.950

cysU

0.937

Your Current Organism:

Mesorhizobium sp. ORS3359

NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPLA_1650119	MPLA_1650121	MPLA_1650119	MPLA_1650121	Sulfite reductase hemoprotein subunit.	Uncharacterized protein.	0.991
MPLA_1650119	cysA	MPLA_1650119	MPLA_100030	Sulfite reductase hemoprotein subunit.	Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.	0.888
MPLA_1650119	cysD	MPLA_1650119	MPLA_1800125	Sulfite reductase hemoprotein subunit.	Sulfate adenylyltransferase subunit 2.	0.950
MPLA_1650119	cysG	MPLA_1650119	MPLA_1650117	Sulfite reductase hemoprotein subunit.	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.	0.994
MPLA_1650119	cysH	MPLA_1650119	MPLA_1650120	Sulfite reductase hemoprotein subunit.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.999
MPLA_1650119	cysP	MPLA_1650119	MPLA_100029	Sulfite reductase hemoprotein subunit.	Thiosulfate transporter subunit periplasmic-binding component of ABC superfamily.	0.859
MPLA_1650119	cysU	MPLA_1650119	MPLA_100032	Sulfite reductase hemoprotein subunit.	Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.	0.784
MPLA_1650119	cysW	MPLA_1650119	MPLA_100031	Sulfite reductase hemoprotein subunit.	Sulfate/thiosulfate permease W protein (ABC superfamily, membrane).	0.855
MPLA_1650119	nodQ	MPLA_1650119	MPLA_1800126	Sulfite reductase hemoprotein subunit.	Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.	0.996
MPLA_1650121	MPLA_1650119	MPLA_1650121	MPLA_1650119	Uncharacterized protein.	Sulfite reductase hemoprotein subunit.	0.991
MPLA_1650121	MPLA_20057	MPLA_1650121	MPLA_20057	Uncharacterized protein.	Cobalamin synthesis protein CobG.	0.912
MPLA_1650121	cysA	MPLA_1650121	MPLA_100030	Uncharacterized protein.	Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.	0.683
MPLA_1650121	cysD	MPLA_1650121	MPLA_1800125	Uncharacterized protein.	Sulfate adenylyltransferase subunit 2.	0.849
MPLA_1650121	cysG	MPLA_1650121	MPLA_1650117	Uncharacterized protein.	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.	0.753
MPLA_1650121	cysH	MPLA_1650121	MPLA_1650120	Uncharacterized protein.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.950
MPLA_1650121	cysU	MPLA_1650121	MPLA_100032	Uncharacterized protein.	Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.	0.535
MPLA_1650121	cysW	MPLA_1650121	MPLA_100031	Uncharacterized protein.	Sulfate/thiosulfate permease W protein (ABC superfamily, membrane).	0.429
MPLA_1650121	nodQ	MPLA_1650121	MPLA_1800126	Uncharacterized protein.	Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.	0.960
MPLA_20057	MPLA_1650121	MPLA_20057	MPLA_1650121	Cobalamin synthesis protein CobG.	Uncharacterized protein.	0.912
MPLA_20057	cysA	MPLA_20057	MPLA_100030	Cobalamin synthesis protein CobG.	Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.	0.888