Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrCThreonine synthase. (477 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase.
 
 0.969
ilvA
L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
 
 0.958
thrB
Homoserine kinase; Belongs to the pseudomonas-type ThrB family.
    
 0.947
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 0.929
MPLA_220048
PALP domain-containing protein.
 
 
 0.894
SRY
Threo-3-hydroxyaspartate ammonia-lyase.
 
 
 0.893
MPLA_1360012
Putative threonine dehydratase.
 
 
 0.893
lysC
Aspartokinase; Belongs to the aspartokinase family.
  
 0.891
ltaE
L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
    
 0.885
MPLA_1800162
Pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.878
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
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