Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
frkFructokinase; Belongs to the carbohydrate kinase PfkB family. (307 aa)    
Predicted Functional Partners:
aglA-2
Putative alpha-glucosidase.
 
  
 0.889
mtlK
Mannitol 2-dehydrogenase; Belongs to the mannitol dehydrogenase family.
 
  
 0.880
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.879
aglA
Putative alpha-glucosidase.
 
  
 0.876
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
  
  
 0.872
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 0.856
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.855
MPLA_1800131
ROK family protein.
 
 
  0.849
MPLA_1100047
Glucosamine-fructose-6-phosphate aminotransferase.
  
 
  0.835
MPLA_1170054
PTS system fructose subfamily IIA component.
    
 0.830
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
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