glnE protein (Mesorhizobium sp. ORS3359) - STRING interaction network

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glnE

Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (993 aa)

Predicted Functional Partners:

gltB

0.858

glnD

0.817

bcp

0.678

MPLA_1800234

0.671

MPLA_1800233

0.578

MPLA_1800149

0.554

nadE

0.554

glnA

0.520

MPLA_720057

0.515

MPLA_100050

0.509

Your Current Organism:

Mesorhizobium sp. ORS3359

NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPLA_100050	glnA	MPLA_100050	MPLA_1830043	Dihydropyrimidine dehydrogenase subunit A.	Glutamine synthetase.	0.575
MPLA_100050	glnE	MPLA_100050	MPLA_1800235	Dihydropyrimidine dehydrogenase subunit A.	Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...]	0.509
MPLA_100050	gltB	MPLA_100050	MPLA_140317	Dihydropyrimidine dehydrogenase subunit A.	Glutamate synthase, large subunit.	0.999
MPLA_100050	nadE	MPLA_100050	MPLA_30016	Dihydropyrimidine dehydrogenase subunit A.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.546
MPLA_1800149	MPLA_1800233	MPLA_1800149	MPLA_1800233	PAS sensor protein.	annotation not available	0.900
MPLA_1800149	MPLA_1800234	MPLA_1800149	MPLA_1800234	PAS sensor protein.	Integral membrane sensor signal transduction histidine kinase.	0.929
MPLA_1800149	MPLA_720057	MPLA_1800149	MPLA_720057	PAS sensor protein.	Histidine kinase.	0.999
MPLA_1800149	glnE	MPLA_1800149	MPLA_1800235	PAS sensor protein.	Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...]	0.554
MPLA_1800149	gltB	MPLA_1800149	MPLA_140317	PAS sensor protein.	Glutamate synthase, large subunit.	0.512
MPLA_1800149	nadE	MPLA_1800149	MPLA_30016	PAS sensor protein.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.588
MPLA_1800233	MPLA_1800149	MPLA_1800233	MPLA_1800149	annotation not available	PAS sensor protein.	0.900
MPLA_1800233	MPLA_1800234	MPLA_1800233	MPLA_1800234	annotation not available	Integral membrane sensor signal transduction histidine kinase.	0.967
MPLA_1800233	MPLA_720057	MPLA_1800233	MPLA_720057	annotation not available	Histidine kinase.	0.899
MPLA_1800233	glnE	MPLA_1800233	MPLA_1800235	annotation not available	Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...]	0.578
MPLA_1800234	MPLA_1800149	MPLA_1800234	MPLA_1800149	Integral membrane sensor signal transduction histidine kinase.	PAS sensor protein.	0.929
MPLA_1800234	MPLA_1800233	MPLA_1800234	MPLA_1800233	Integral membrane sensor signal transduction histidine kinase.	annotation not available	0.967
MPLA_1800234	MPLA_720057	MPLA_1800234	MPLA_720057	Integral membrane sensor signal transduction histidine kinase.	Histidine kinase.	0.795
MPLA_1800234	glnE	MPLA_1800234	MPLA_1800235	Integral membrane sensor signal transduction histidine kinase.	Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...]	0.671
MPLA_720057	MPLA_1800149	MPLA_720057	MPLA_1800149	Histidine kinase.	PAS sensor protein.	0.999
MPLA_720057	MPLA_1800233	MPLA_720057	MPLA_1800233	Histidine kinase.	annotation not available	0.899

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