sgaA protein (Mesorhizobium sp. ORS3359) - STRING interaction network

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Score

sgaA

Serine--glyoxylate aminotransferase. (396 aa)

Predicted Functional Partners:

mcl

0.968

lldD

0.924

MPLA_250024

0.890

gcvP

0.888

glcF

0.877

glyA

0.872

maeB

0.870

maeB-2

0.870

MPLA_810026

0.867

glcB

0.859

Your Current Organism:

Mesorhizobium sp. ORS3359

NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPLA_250024	MPLA_810026	MPLA_250024	MPLA_810026	Phosphoserine phosphatase SerB.	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.511
MPLA_250024	glyA	MPLA_250024	MPLA_1550035	Phosphoserine phosphatase SerB.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.963
MPLA_250024	lldD	MPLA_250024	MPLA_1650073	Phosphoserine phosphatase SerB.	L-lactate dehydrogenase, FMN-linked.	0.485
MPLA_250024	sgaA	MPLA_250024	MPLA_20024	Phosphoserine phosphatase SerB.	Serine--glyoxylate aminotransferase.	0.890
MPLA_810026	MPLA_250024	MPLA_810026	MPLA_250024	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Phosphoserine phosphatase SerB.	0.511
MPLA_810026	gcvP	MPLA_810026	MPLA_290003	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.806
MPLA_810026	glcB	MPLA_810026	MPLA_850001	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.848
MPLA_810026	glcF	MPLA_810026	MPLA_1650082	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycolate oxidase iron-sulfur subunit.	0.842
MPLA_810026	lldD	MPLA_810026	MPLA_1650073	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	L-lactate dehydrogenase, FMN-linked.	0.555
MPLA_810026	maeB	MPLA_810026	MPLA_50008	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Putative fused malic enzyme oxidoreductase phosphotransacetylase.	0.815
MPLA_810026	maeB-2	MPLA_810026	MPLA_630023	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Putative fused malic enzyme oxidoreductase phosphotransacetylase.	0.815
MPLA_810026	mcl	MPLA_810026	MPLA_20025	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.	0.881
MPLA_810026	sgaA	MPLA_810026	MPLA_20024	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Serine--glyoxylate aminotransferase.	0.867
gcvP	MPLA_810026	MPLA_290003	MPLA_810026	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.806
gcvP	glcF	MPLA_290003	MPLA_1650082	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Glycolate oxidase iron-sulfur subunit.	0.703
gcvP	glyA	MPLA_290003	MPLA_1550035	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.991
gcvP	lldD	MPLA_290003	MPLA_1650073	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	L-lactate dehydrogenase, FMN-linked.	0.626
gcvP	maeB	MPLA_290003	MPLA_50008	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Putative fused malic enzyme oxidoreductase phosphotransacetylase.	0.424
gcvP	maeB-2	MPLA_290003	MPLA_630023	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Putative fused malic enzyme oxidoreductase phosphotransacetylase.	0.424
gcvP	sgaA	MPLA_290003	MPLA_20024	Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine--glyoxylate aminotransferase.	0.888