| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_20063 | cobB | MPLA_20063 | MPLA_20066 | Cobalamin biosynthesis protein G CbiG. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.958 |
| MPLA_20063 | cobF | MPLA_20063 | MPLA_250032 | Cobalamin biosynthesis protein G CbiG. | Precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.949 |
| MPLA_20063 | cobH | MPLA_20063 | MPLA_20058 | Cobalamin biosynthesis protein G CbiG. | Precorrin-8X methylmutase. | 0.974 |
| MPLA_20063 | cobI | MPLA_20063 | MPLA_20059 | Cobalamin biosynthesis protein G CbiG. | Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.963 |
| MPLA_20063 | cobJ | MPLA_20063 | MPLA_20060 | Cobalamin biosynthesis protein G CbiG. | Precorrin-3B C(17)-methyltransferase. | 0.979 |
| MPLA_20063 | cobK | MPLA_20063 | MPLA_20061 | Cobalamin biosynthesis protein G CbiG. | Precorrin-6A reductase. | 0.988 |
| MPLA_20063 | cobL | MPLA_20063 | MPLA_20062 | Cobalamin biosynthesis protein G CbiG. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.998 |
| MPLA_20063 | cobM | MPLA_20063 | MPLA_20064 | Cobalamin biosynthesis protein G CbiG. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.998 |
| MPLA_20063 | cobQ | MPLA_20063 | MPLA_320141 | Cobalamin biosynthesis protein G CbiG. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.744 |
| MPLA_20063 | cobS | MPLA_20063 | MPLA_20067 | Cobalamin biosynthesis protein G CbiG. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.885 |
| cobB | MPLA_20063 | MPLA_20066 | MPLA_20063 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein G CbiG. | 0.958 |
| cobB | cobF | MPLA_20066 | MPLA_250032 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.744 |
| cobB | cobH | MPLA_20066 | MPLA_20058 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-8X methylmutase. | 0.994 |
| cobB | cobI | MPLA_20066 | MPLA_20059 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.887 |
| cobB | cobJ | MPLA_20066 | MPLA_20060 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-3B C(17)-methyltransferase. | 0.959 |
| cobB | cobK | MPLA_20066 | MPLA_20061 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6A reductase. | 0.945 |
| cobB | cobL | MPLA_20066 | MPLA_20062 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.979 |
| cobB | cobM | MPLA_20066 | MPLA_20064 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.980 |
| cobB | cobQ | MPLA_20066 | MPLA_320141 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.984 |
| cobB | cobS | MPLA_20066 | MPLA_20067 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.971 |