| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | cobJ | MPLA_20066 | MPLA_20060 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-3B C(17)-methyltransferase. | 0.959 |
| cobB | cobK | MPLA_20066 | MPLA_20061 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6A reductase. | 0.945 |
| cobB | cobL | MPLA_20066 | MPLA_20062 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.979 |
| cobB | cobM | MPLA_20066 | MPLA_20064 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.980 |
| cobB | cobO | MPLA_20066 | MPLA_20014 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.974 |
| cobB | cobQ | MPLA_20066 | MPLA_320141 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.984 |
| cobB | cobS | MPLA_20066 | MPLA_20067 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.971 |
| cobB | cobT | MPLA_20066 | MPLA_1830172 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase. | 0.861 |
| cobB | cobT-2 | MPLA_20066 | MPLA_20068 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.974 |
| cobB | cobU | MPLA_20066 | MPLA_20015 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.973 |
| cobJ | cobB | MPLA_20060 | MPLA_20066 | Precorrin-3B C(17)-methyltransferase. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.959 |
| cobJ | cobK | MPLA_20060 | MPLA_20061 | Precorrin-3B C(17)-methyltransferase. | Precorrin-6A reductase. | 0.995 |
| cobJ | cobL | MPLA_20060 | MPLA_20062 | Precorrin-3B C(17)-methyltransferase. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.998 |
| cobJ | cobM | MPLA_20060 | MPLA_20064 | Precorrin-3B C(17)-methyltransferase. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
| cobJ | cobO | MPLA_20060 | MPLA_20014 | Precorrin-3B C(17)-methyltransferase. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.757 |
| cobJ | cobQ | MPLA_20060 | MPLA_320141 | Precorrin-3B C(17)-methyltransferase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| cobJ | cobS | MPLA_20060 | MPLA_20067 | Precorrin-3B C(17)-methyltransferase. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.967 |
| cobJ | cobT | MPLA_20060 | MPLA_1830172 | Precorrin-3B C(17)-methyltransferase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase. | 0.665 |
| cobJ | cobT-2 | MPLA_20060 | MPLA_20068 | Precorrin-3B C(17)-methyltransferase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.693 |
| cobJ | cobU | MPLA_20060 | MPLA_20015 | Precorrin-3B C(17)-methyltransferase. | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.890 |