| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_1800033 | cobB | MPLA_1800033 | MPLA_20066 | Cob(II)yrinic acid a,c-diamide reductase. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.862 |
| MPLA_1800033 | cobC | MPLA_1800033 | MPLA_20011 | Cob(II)yrinic acid a,c-diamide reductase. | Threonine-phosphate decarboxylase. | 0.742 |
| MPLA_1800033 | cobD | MPLA_1800033 | MPLA_20012 | Cob(II)yrinic acid a,c-diamide reductase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.541 |
| MPLA_1800033 | cobL | MPLA_1800033 | MPLA_20062 | Cob(II)yrinic acid a,c-diamide reductase. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.668 |
| MPLA_1800033 | cobM | MPLA_1800033 | MPLA_20064 | Cob(II)yrinic acid a,c-diamide reductase. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.611 |
| MPLA_1800033 | cobQ | MPLA_1800033 | MPLA_320141 | Cob(II)yrinic acid a,c-diamide reductase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.549 |
| MPLA_1800033 | cobS | MPLA_1800033 | MPLA_20067 | Cob(II)yrinic acid a,c-diamide reductase. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.754 |
| MPLA_1800033 | cobT | MPLA_1800033 | MPLA_1830172 | Cob(II)yrinic acid a,c-diamide reductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase. | 0.984 |
| MPLA_1800033 | cobT-2 | MPLA_1800033 | MPLA_20068 | Cob(II)yrinic acid a,c-diamide reductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.992 |
| MPLA_1800033 | cobU | MPLA_1800033 | MPLA_20015 | Cob(II)yrinic acid a,c-diamide reductase. | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.890 |
| cobB | MPLA_1800033 | MPLA_20066 | MPLA_1800033 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cob(II)yrinic acid a,c-diamide reductase. | 0.862 |
| cobB | cobC | MPLA_20066 | MPLA_20011 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Threonine-phosphate decarboxylase. | 0.775 |
| cobB | cobD | MPLA_20066 | MPLA_20012 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.927 |
| cobB | cobL | MPLA_20066 | MPLA_20062 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating). | 0.979 |
| cobB | cobM | MPLA_20066 | MPLA_20064 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.980 |
| cobB | cobQ | MPLA_20066 | MPLA_320141 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.984 |
| cobB | cobS | MPLA_20066 | MPLA_20067 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.971 |
| cobB | cobT | MPLA_20066 | MPLA_1830172 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase. | 0.861 |
| cobB | cobT-2 | MPLA_20066 | MPLA_20068 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.974 |
| cobB | cobU | MPLA_20066 | MPLA_20015 | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.973 |