Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MPLA_240008Transcriptional regulator. (217 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.771
MPLA_1830096
Uncharacterized protein.
  
     0.513
MPLA_240010
Rieske domain-containing protein.
 
     0.504
MPLA_240009
Putative transcriptional regulator.
       0.496
MPLA_1830134
DUF2059 domain-containing protein.
  
     0.471
MPLA_430032
DUF1737 domain-containing protein.
  
    0.471
MPLA_1800072
Uncharacterized protein.
  
     0.462
MPLA_1800215
DUF1254 domain-containing protein.
  
     0.426
MPLA_1550004
RDD domain-containing protein.
  
     0.424
MPLA_1720003
Plasmid stabilization system.
  
     0.401
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
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