STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobFPrecorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. (254 aa)    
Predicted Functional Partners:
cobM
Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.997
cobK
Precorrin-6A reductase.
 
 
 0.995
cobL
Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating).
 
 
 0.994
cobH
Precorrin-8X methylmutase.
 
 
 0.986
cobJ
Precorrin-3B C(17)-methyltransferase.
 
 
 0.986
MPLA_20063
Cobalamin biosynthesis protein G CbiG.
  
 
 0.943
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.895
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
    
 0.881
MPLA_20057
Cobalamin synthesis protein CobG.
 
 
 0.828
cobB
Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.809
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
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