Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPLA_270005Cytochrome c biogenesis protein transmembrane region. (248 aa)    
Predicted Functional Partners:
tlpA
Thiol:disulfide interchange protein tlpA.
 
  
 0.652
ccmG
Periplasmic thioredoxin of cytochrome c-type biogenesis.
 
  
 0.604
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.522
MPLA_270006
Uncharacterized protein.
       0.515
MPLA_2130089
Recombinase.
   
    0.511
MPLA_380028
Resolvase, N-terminal domain.
   
    0.511
MPLA_860013
Uncharacterized protein.
   
    0.511
MPLA_270007
Uncharacterized protein.
       0.505
actP
Copper-transporting P-type ATPase.
 
   
 0.469
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
  
 0.418
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
Server load: low (24%) [HD]