murI protein (Mesorhizobium sp. ORS3359) - STRING interaction network

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Score

murI

Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)

Predicted Functional Partners:

murD

0.980

yneH

0.908

murE

0.820

murC

0.807

MPLA_1650028

0.799

murF

0.684

guaA

0.663

guaB

0.629

truA

0.582

gltB

0.568

Your Current Organism:

Mesorhizobium sp. ORS3359

NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPLA_1650028	guaA	MPLA_1650028	MPLA_1650100	Mur ligase middle domain protein.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.435
MPLA_1650028	murC	MPLA_1650028	MPLA_1190101	Mur ligase middle domain protein.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.978
MPLA_1650028	murD	MPLA_1650028	MPLA_1190098	Mur ligase middle domain protein.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.988
MPLA_1650028	murE	MPLA_1650028	MPLA_1190095	Mur ligase middle domain protein.	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.989
MPLA_1650028	murF	MPLA_1650028	MPLA_1190096	Mur ligase middle domain protein.	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.	0.836
MPLA_1650028	murI	MPLA_1650028	MPLA_30101	Mur ligase middle domain protein.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.799
gltB	guaA	MPLA_140317	MPLA_1650100	Glutamate synthase, large subunit.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.976
gltB	guaB	MPLA_140317	MPLA_1540004	Glutamate synthase, large subunit.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.845
gltB	murD	MPLA_140317	MPLA_1190098	Glutamate synthase, large subunit.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.511
gltB	murE	MPLA_140317	MPLA_1190095	Glutamate synthase, large subunit.	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.519
gltB	murI	MPLA_140317	MPLA_30101	Glutamate synthase, large subunit.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.568
gltB	yneH	MPLA_140317	MPLA_230010	Glutamate synthase, large subunit.	Glutaminase; Belongs to the glutaminase family.	0.930
guaA	MPLA_1650028	MPLA_1650100	MPLA_1650028	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Mur ligase middle domain protein.	0.435
guaA	gltB	MPLA_1650100	MPLA_140317	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase, large subunit.	0.976
guaA	guaB	MPLA_1650100	MPLA_1540004	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	murC	MPLA_1650100	MPLA_1190101	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.472
guaA	murD	MPLA_1650100	MPLA_1190098	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.459
guaA	murE	MPLA_1650100	MPLA_1190095	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.430
guaA	murI	MPLA_1650100	MPLA_30101	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.663
guaA	truA	MPLA_1650100	MPLA_860022	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.565