STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
MPLA_3201443-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (294 aa)    
Predicted Functional Partners:
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.
 
  0.969
acad
Isobutyryl-CoA dehydrogenase, mitochondrial.
 
 
  0.880
MPLA_580001
Methylmalonate-semialdehyde dehydrogenase.
  
 
  0.873
MPLA_1590005
6-phosphogluconate dehydrogenase NAD-binding protein.
  
  
 
0.866
MPLA_1830161
Uncharacterized oxidoreductase Sfri_1503.
  
  
 
0.863
Pcca
Propionyl-CoA carboxylase alpha chain, mitochondrial.
  
 
  0.848
MPLA_1320018
AMP-dependent synthetase and ligase.
  
 
  0.835
prpE
Propionyl-CoA synthetase.
  
 
  0.835
acsA-3
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.835
MPLA_1110003
Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.833
Your Current Organism:
Mesorhizobium sp. ORS3359
NCBI taxonomy Id: 408184
Other names: M. sp. ORS 3359, Mesorhizobium sp. ORS 3359
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