| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_90090 | purA | MPLA_90090 | MPLA_590020 | 3-carboxy-cis,cis-muconate cycloisomerase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.981 |
| MPLA_90090 | purB | MPLA_90090 | MPLA_30125 | 3-carboxy-cis,cis-muconate cycloisomerase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.637 |
| MPLA_90090 | purC-2 | MPLA_90090 | MPLA_320190 | 3-carboxy-cis,cis-muconate cycloisomerase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.981 |
| MPLA_90090 | purD | MPLA_90090 | MPLA_1800003 | 3-carboxy-cis,cis-muconate cycloisomerase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.987 |
| MPLA_90090 | purE | MPLA_90090 | MPLA_180044 | 3-carboxy-cis,cis-muconate cycloisomerase. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.989 |
| MPLA_90090 | purF | MPLA_90090 | MPLA_1250004 | 3-carboxy-cis,cis-muconate cycloisomerase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.974 |
| MPLA_90090 | purH | MPLA_90090 | MPLA_550001 | 3-carboxy-cis,cis-muconate cycloisomerase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.979 |
| MPLA_90090 | purK | MPLA_90090 | MPLA_180045 | 3-carboxy-cis,cis-muconate cycloisomerase. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.980 |
| MPLA_90090 | purM | MPLA_90090 | MPLA_1280067 | 3-carboxy-cis,cis-muconate cycloisomerase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.973 |
| MPLA_90090 | purN | MPLA_90090 | MPLA_1280066 | 3-carboxy-cis,cis-muconate cycloisomerase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.949 |
| purA | MPLA_90090 | MPLA_590020 | MPLA_90090 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 3-carboxy-cis,cis-muconate cycloisomerase. | 0.981 |
| purA | purB | MPLA_590020 | MPLA_30125 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.998 |
| purA | purC-2 | MPLA_590020 | MPLA_320190 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.964 |
| purA | purD | MPLA_590020 | MPLA_1800003 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.915 |
| purA | purE | MPLA_590020 | MPLA_180044 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.978 |
| purA | purF | MPLA_590020 | MPLA_1250004 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.905 |
| purA | purH | MPLA_590020 | MPLA_550001 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.983 |
| purA | purK | MPLA_590020 | MPLA_180045 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.973 |
| purA | purM | MPLA_590020 | MPLA_1280067 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.799 |
| purA | purN | MPLA_590020 | MPLA_1280066 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.972 |