| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MPLA_320191 | apt | MPLA_320191 | MPLA_900001 | Peptidase, M50 family protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.607 |
| MPLA_320191 | gpt | MPLA_320191 | MPLA_30021 | Peptidase, M50 family protein. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.607 |
| MPLA_320191 | guaA | MPLA_320191 | MPLA_1650100 | Peptidase, M50 family protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.889 |
| MPLA_320191 | guaB | MPLA_320191 | MPLA_1540004 | Peptidase, M50 family protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.579 |
| MPLA_320191 | hpt | MPLA_320191 | MPLA_220041 | Peptidase, M50 family protein. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.563 |
| MPLA_320191 | purA | MPLA_320191 | MPLA_590020 | Peptidase, M50 family protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.595 |
| MPLA_320191 | purC-2 | MPLA_320191 | MPLA_320190 | Peptidase, M50 family protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.601 |
| MPLA_320191 | purH | MPLA_320191 | MPLA_550001 | Peptidase, M50 family protein. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.581 |
| MPLA_320191 | surE | MPLA_320191 | MPLA_310019 | Peptidase, M50 family protein. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.588 |
| MPLA_320191 | yehZ | MPLA_320191 | MPLA_1550044 | Peptidase, M50 family protein. | Putative transporter subunit: periplasmic-binding component of ABC superfamily. | 0.574 |
| apt | MPLA_320191 | MPLA_900001 | MPLA_320191 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Peptidase, M50 family protein. | 0.607 |
| apt | gpt | MPLA_900001 | MPLA_30021 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.601 |
| apt | guaA | MPLA_900001 | MPLA_1650100 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.948 |
| apt | guaB | MPLA_900001 | MPLA_1540004 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.813 |
| apt | hpt | MPLA_900001 | MPLA_220041 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.713 |
| apt | purA | MPLA_900001 | MPLA_590020 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.780 |
| apt | purH | MPLA_900001 | MPLA_550001 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.941 |
| apt | surE | MPLA_900001 | MPLA_310019 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.868 |
| gpt | MPLA_320191 | MPLA_30021 | MPLA_320191 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Peptidase, M50 family protein. | 0.607 |
| gpt | apt | MPLA_30021 | MPLA_900001 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.601 |