STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC10421731111-beta-hydroxysteroid dehydrogenase 1B-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (353 aa)    
Predicted Functional Partners:
LOC104226167
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
   
 
 0.550
LOC104246758
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
   
 
 0.550
LOC104219342
Transcription factor HY5 isoform X1.
    
 
 0.547
LOC104237777
Uncharacterized protein LOC104237777.
    
 
 0.547
LOC104246095
Uncharacterized protein LOC104246095.
    
 
 0.547
LOC104248364
malonyl-CoA-acyl carrier protein transacylase, mitochondrial.
  
 
 0.496
LOC104249474
Alkyl transferase; Belongs to the UPP synthase family.
      
 0.482
LOC104216533
Putative acyl-activating enzyme 19 isoform X1.
  
 0.455
LOC104239913
DNA-damage-repair/toleration protein DRT102.
  
 
 0.417
LOC104210745
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
  
 0.402
Your Current Organism:
Nicotiana sylvestris
NCBI taxonomy Id: 4096
Other names: N. sylvestris, Nicotiana sylvestris Speg. & Comes, wood tobacco
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