STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYS5Cysteine proteinase inhibitor 5-like; Belongs to the cystatin family. (123 aa)    
Predicted Functional Partners:
PRO3
Profilin-3; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
      
 0.751
LTP1
Non-specific lipid-transfer protein 1; Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. Binds cis- unsaturated fatty acids and jasmonic acid with a higher affinity than linear chain fatty acids. Formation of the complex with jasmonic acid results in a conformational change facilitating the LPT1 binding on the elicitin plasma membrane receptor that is known to be involved in plant defense induction. May also play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
      
 0.630
LOC107777553
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
      
 0.524
LOC107780759
Non-specific lipid-transfer protein 1-like; Belongs to the plant LTP family.
      
 0.416
LOC107791195
Glycerophosphodiester phosphodiesterase GDPD6-like.
      
 0.412
LOC107826889
Glycerophosphodiester phosphodiesterase GDPD6-like isoform X1.
      
 0.412
PRO2
Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
      
 0.410
Your Current Organism:
Nicotiana tabacum
NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco
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