STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107759854E2F transcription factor-like E2FE. (374 aa)    
Predicted Functional Partners:
LOC107770785
Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
    
 
 0.676
LOC107804732
Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
    
 
 0.676
LOC107777437
Retinoblastoma-related protein 1 isoform X1.
    
 
 0.647
LOC107801954
Retinoblastoma-related protein 1-like.
    
 
 0.647
RB1
Retinoblastoma-related protein 1; Regulator of biological processes that recruits a histone deacetylase to control gene transcription. May play a role in the entry into mitosis, negatively regulating the cell proliferation. Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity); Belongs to the retinoblastoma protein (RB) family.
    
 
 0.647
LOC107816960
Serine/threonine-protein kinase mph1-like.
   
  
 0.509
LOC107819235
Serine/threonine-protein kinase mph1.
   
  
 0.509
LOC107831452
Serine/threonine-protein kinase mph1-like.
   
  
 0.509
LOC107780802
Cell division control protein; Belongs to the CDC6/cdc18 family.
   
  
 0.500
LOC107789612
Cell division control protein; Belongs to the CDC6/cdc18 family.
   
  
 0.500
Your Current Organism:
Nicotiana tabacum
NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.