STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMGP00000000599SPO11 initiator of meiotic double stranded breaks. (368 aa)    
Predicted Functional Partners:
ENSPMGP00000029640
WD repeat domain 61.
    
 
 0.940
ENSPMGP00000027563
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
    
 0.912
ENSPMGP00000023182
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 0.876
ENSPMGP00000003418
RAD51 paralog C.
    
 0.864
ENSPMGP00000022927
RECA_2 domain-containing protein.
    
 0.864
ENSPMGP00000015194
RECA_2 domain-containing protein.
    
 0.858
ENSPMGP00000024148
RAD50 homolog, double strand break repair protein.
    
 0.853
ENSPMGP00000003462
MUS81 structure-specific endonuclease subunit.
   
 
 0.835
ENSPMGP00000006059
5-aminolevulinate synthase.
    
  0.807
ENSPMGP00000006362
5-aminolevulinate synthase.
    
  0.807
Your Current Organism:
Periophthalmus magnuspinnatus
NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus
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