Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C1orf43Chromosome 1 open reading frame 43. (248 aa)    
Predicted Functional Partners:
ENSPMGP00000000414
ER membrane protein complex subunit 7.
      
 0.733
ENSPMGP00000010755
Proteasome subunit beta; Belongs to the peptidase T1B family.
   
  
 0.705
ENSPMGP00000028179
Uncharacterized protein.
    
 
 0.687
ENSPMGP00000028189
Uncharacterized protein.
    
 
 0.687
ENSPMGP00000028198
FSA_C domain-containing protein.
    
 
 0.687
ENSPMGP00000028201
FSA_C domain-containing protein.
    
 
 0.687
EDF1
Endothelial differentiation related factor 1.
      
 0.687
ENSPMGP00000004602
Charged multivesicular body protein 2A.
      
 0.651
PRIMA1
Proline rich membrane anchor 1.
      
 0.638
ENSPMGP00000003857
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
  
 0.614
Your Current Organism:
Periophthalmus magnuspinnatus
NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.