STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMGP00000007765MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (158 aa)    
Predicted Functional Partners:
ENSPMGP00000000838
Intersectin 2a.
    
 0.996
ENSPMGP00000002292
Uncharacterized protein.
    
 0.996
ENSPMGP00000002296
Uncharacterized protein.
    
 0.996
ENSPMGP00000016880
Intersectin 1 (SH3 domain protein).
    
 0.897
ENSPMGP00000022199
C2 domain-containing protein.
    
 0.897
ENSPMGP00000009826
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.877
ENSPMGP00000003857
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.876
ENSPMGP00000027416
Epidermal growth factor receptor pathway substrate 15.
    
 0.810
ENSPMGP00000025632
AP-1 complex subunit gamma; Belongs to the adaptor complexes large subunit family.
    
 0.764
ENSPMGP00000025638
Uncharacterized protein.
    
 0.764
Your Current Organism:
Periophthalmus magnuspinnatus
NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.