node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COPS6 | ENSPMGP00000003987 | ENSPMGP00000024948 | ENSPMGP00000003987 | COP9 signalosome subunit 6. | SUMO peptidase family member, NEDD8 specific. | 0.580 |
COPS6 | ENSPMGP00000009851 | ENSPMGP00000024948 | ENSPMGP00000009851 | COP9 signalosome subunit 6. | Cullin 1b; Belongs to the cullin family. | 0.924 |
COPS6 | ENSPMGP00000013487 | ENSPMGP00000024948 | ENSPMGP00000013487 | COP9 signalosome subunit 6. | Cullin 2; Belongs to the cullin family. | 0.966 |
COPS6 | ENSPMGP00000016076 | ENSPMGP00000024948 | ENSPMGP00000016076 | COP9 signalosome subunit 6. | Myb-like, SWIRM and MPN domains 1. | 0.590 |
COPS6 | ENSPMGP00000017027 | ENSPMGP00000024948 | ENSPMGP00000017027 | COP9 signalosome subunit 6. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.711 |
COPS6 | ENSPMGP00000017325 | ENSPMGP00000024948 | ENSPMGP00000017325 | COP9 signalosome subunit 6. | UBX domain protein 7. | 0.765 |
COPS6 | ENSPMGP00000022075 | ENSPMGP00000024948 | ENSPMGP00000022075 | COP9 signalosome subunit 6. | Ring-box 1, E3 ubiquitin protein ligase. | 0.969 |
COPS6 | ENSPMGP00000023295 | ENSPMGP00000024948 | ENSPMGP00000023295 | COP9 signalosome subunit 6. | Ubiquitin-like domain-containing protein. | 0.982 |
COPS6 | ENSPMGP00000029594 | ENSPMGP00000024948 | ENSPMGP00000029594 | COP9 signalosome subunit 6. | COP9 signalosome subunit 5. | 0.998 |
COPS6 | UBA3 | ENSPMGP00000024948 | ENSPMGP00000019145 | COP9 signalosome subunit 6. | Ubiquitin like modifier activating enzyme 3. | 0.682 |
ENSPMGP00000003987 | COPS6 | ENSPMGP00000003987 | ENSPMGP00000024948 | SUMO peptidase family member, NEDD8 specific. | COP9 signalosome subunit 6. | 0.580 |
ENSPMGP00000003987 | ENSPMGP00000009851 | ENSPMGP00000003987 | ENSPMGP00000009851 | SUMO peptidase family member, NEDD8 specific. | Cullin 1b; Belongs to the cullin family. | 0.682 |
ENSPMGP00000003987 | ENSPMGP00000013487 | ENSPMGP00000003987 | ENSPMGP00000013487 | SUMO peptidase family member, NEDD8 specific. | Cullin 2; Belongs to the cullin family. | 0.507 |
ENSPMGP00000003987 | ENSPMGP00000016076 | ENSPMGP00000003987 | ENSPMGP00000016076 | SUMO peptidase family member, NEDD8 specific. | Myb-like, SWIRM and MPN domains 1. | 0.689 |
ENSPMGP00000003987 | ENSPMGP00000017027 | ENSPMGP00000003987 | ENSPMGP00000017027 | SUMO peptidase family member, NEDD8 specific. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.844 |
ENSPMGP00000003987 | ENSPMGP00000023295 | ENSPMGP00000003987 | ENSPMGP00000023295 | SUMO peptidase family member, NEDD8 specific. | Ubiquitin-like domain-containing protein. | 0.985 |
ENSPMGP00000003987 | ENSPMGP00000029594 | ENSPMGP00000003987 | ENSPMGP00000029594 | SUMO peptidase family member, NEDD8 specific. | COP9 signalosome subunit 5. | 0.743 |
ENSPMGP00000003987 | UBA3 | ENSPMGP00000003987 | ENSPMGP00000019145 | SUMO peptidase family member, NEDD8 specific. | Ubiquitin like modifier activating enzyme 3. | 0.850 |
ENSPMGP00000009851 | COPS6 | ENSPMGP00000009851 | ENSPMGP00000024948 | Cullin 1b; Belongs to the cullin family. | COP9 signalosome subunit 6. | 0.924 |
ENSPMGP00000009851 | ENSPMGP00000003987 | ENSPMGP00000009851 | ENSPMGP00000003987 | Cullin 1b; Belongs to the cullin family. | SUMO peptidase family member, NEDD8 specific. | 0.682 |