STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B9Z65_5375Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (175 aa)    
Predicted Functional Partners:
B9Z65_3684
Thioredoxin; Belongs to the thioredoxin family.
   
 0.965
B9Z65_8550
Peroxiredoxin TSA1.
   
 0.939
B9Z65_5393
RBR-type E3 ubiquitin transferase.
 
      0.899
B9Z65_5838
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.886
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
    
 0.876
B9Z65_8852
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    
 0.819
B9Z65_6571
Dihydrolipoyl dehydrogenase.
    
 0.750
B9Z65_8603
Mitochondrial peroxiredoxin PRX1.
   
 0.735
B9Z65_6373
Mitochondrial peroxiredoxin PRX1.
   
 0.735
B9Z65_7770
Protein disulfide-isomerase.
   
 0.710
Your Current Organism:
Elsinoe australis
NCBI taxonomy Id: 40998
Other names: E. australis, Sphaceloma australis
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