STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B9Z65_6540Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (618 aa)    
Predicted Functional Partners:
B9Z65_2549
3'-5' exonuclease domain-containing protein.
    
 0.999
B9Z65_3576
Uncharacterized protein.
  
 0.998
B9Z65_7490
Uncharacterized protein.
    
 0.996
B9Z65_7742
ATP-dependent DNA helicase hus2/rqh1.
   
 0.993
B9Z65_2235
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 0.988
B9Z65_4383
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.988
B9Z65_5536
DNA helicase; Belongs to the MCM family.
   
 0.982
B9Z65_8715
DNA repair protein rad16.
    
 0.981
B9Z65_4193
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.980
B9Z65_2463
DNA replication ATP-dependent helicase/nuclease dna2.
    
 0.979
Your Current Organism:
Elsinoe australis
NCBI taxonomy Id: 40998
Other names: E. australis, Sphaceloma australis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.