STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUP30392.1IMP cyclohydrolase. (237 aa)    
Predicted Functional Partners:
purH
Bifunctional purine biosynthesis protein PurH.
 
  
 0.994
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
  0.952
purL
Phosphoribosylformylglycinamidine synthase.
  
 
 0.932
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.906
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 
 0.553
CUP85902.1
Uncharacterised protein.
  
     0.488
CUP30020.1
Predicted membrane protein.
       0.484
ygaZ
Inner membrane protein YgaZ.
       0.484
CUP19132.1
Predicted membrane protein.
  
     0.437
cheY
Chemotaxis protein CheY.
       0.417
Your Current Organism:
Coprococcus comes
NCBI taxonomy Id: 410072
Other names: ATCC 27758, C. comes, VPI C1-38
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.