STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metK_2S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (386 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.863
metH
Methionine synthase.
  
 
 0.854
CUP37931.1
Uncharacterised protein.
       0.773
CUP37958.1
DNA primase (bacterial type).
       0.773
rpfG_2
Cyclic di-GMP phosphodiesterase response regulator RpfG.
    
  0.750
tipA_1
HTH-type transcriptional activator tipA.
    
 0.705
metB
Cystathionine gamma-synthase.
   
 0.701
ribH
6%2C7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
   0.644
hpdA
4-hydroxyphenylacetate decarboxylase activating enzyme.
      
 0.613
metF
5%2C10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.605
Your Current Organism:
Coprococcus comes
NCBI taxonomy Id: 410072
Other names: ATCC 27758, C. comes, VPI C1-38
Server load: low (16%) [HD]